7:00 am – 8:00 am

Breakfast

8:00 am – 10:00 am

Oral Abstract Session 1: Mast Cells

Chair: Daniel F. Dwyer, United States

8:00 am – 8:20 am

Oral Abstract 1: Platelets Engage Mast cells in a Bilateral IL-33-Driven Feed-Forward Loop

Joshua A. Boyce, United States

8:20 am – 8:40 am

Oral Abstract 2: The Context Significance Of CD300a On Mast Cells And Beyond: What Is Its Role In Breast Cancer? A New Immune Checkpoint Inhibitor?

Francesca Levi-Schaffer, Israel

8:40 am – 9:00 am

Oral Abstract 3: IL-33 Unleashes a Proinflammatory Program in Human Lung Mast Cells

Gunnar Nilsson, Sweden

9:00 am – 9:20 am

Oral Abstract 4: Oxysterol Regulation Of Mast Cell Hyperplasia During Allergic Lung Inflammation

Daniel F. Dwyer, United States

9:20 am – 9:40 am

Oral Abstract 5: Lung Compartment Specific Mast Cell Heterogeneity

Elin Rönnberg Höckerlind, Sweden

9:40 am – 10:00 am

Oral Abstract 6: Mast Cells Both Enhance Early Effective Immunity And Promote Eosinophil Accumulation In A Model Of Respiratory Syncytial Virus Infection

Jean S. Marshall, Canada

10:00 – 10:30 am

Break

10:30 am – 11:50 am

Oral Abstract Session 2: Pathophysiology of Allergic Inflammation 1

Chair:  Angela Haczku, United States

10:30 am – 10:50 am

Oral Abstract 7: Maternal Stress Triggers Early-Life Eczema via Fetal Mast Cell Programming

Nicolas Gaudenzio, France

10:50 am – 11:10 am

Oral Abstract 8: Interplay Between Type (1) and Type 2 (T2) Immune Responses and Asthma Severity

Anuradha Ray, United States

11:10 am – 11:30 am

Oral Abstract 9: Maternal DHET of Allergic Mothers Increases Allergen Responsiveness in Offspring

Joan M. Cook-Mills, United States

11:30 am – 11:50 am

Oral Abstract 10: Fecal Products From 1 Mo-Old Infants at Increased Risk of Asthma Activate a Novel B Cell/IL17/Neutrophil Axis That Promotes Lung Inflammation

Avery DeVries, United States

11:50 am – 1:15 pm

Lunch

12:00 pm – 1:00 pm

Satellite Symposium: Interconnectivity of Type 2 Inflammation Across Select Diseases

Speaker: Leonard Bacharier, United States

This non-CME event, sponsored by Regeneron, is open to the first 50 participants and includes lunch.

Regulation of Type 2 Inflammation

David Artis, United Kingdom

2:00 pm – 3:20 pm

Oral Abstract Session 3: Environmental Factors

Chair:  Steve N. Georas, United States

2:00 pm – 2:20 pm

Oral Abstract 11: Impact of Early-Life Respiratory Syncytial Virus Infection on Airway Epithelial Cell-Specific DNA Methylation and Recurrent Wheeze in Early Childhood

Tina Hartert, United States

2:20 pm – 2:40 pm

Oral Abstract 12: Airway Treatment with Amish Farm Dust Extracts Protects against Acute Airway Rhinovirus Infection and Induces Enduring Anti-Viral Immune Training

Donata Vercelli, United States

2:40 pm – 3:00 pm

Oral Abstract 13: Farm Exposure Protects From Childhood Asthma Through Nine Gram-Positive Bacterial Genera

Erika Von Mutius, Germany

3:00 pm – 3:20 pm

Oral Abstract 14: Farm Exposure is Associated With Human Milk Immune Profile and Microbiota

Anne Marie Singh, United States

3:20 pm – 4:00 pm

Break

Allergic to Literature? Healing Beyond the Prescription Pad

Karolina Lisak Vidović, Croatia

5:00 pm – 5:30 pm

Poster Lightning Round 1

Chair:  Kenji Kabashima, Japan

5:00 pm – 5:05 pm

Lightning Poster 1:  Grass Pollen Sublingual Tablet Immunotherapy Plus Dupilumab for Induction of Tolerance in Adults with Moderate to Severe Seasonal Allergic Rhinitis

Stephen R. Durham, United Kingdom

5:05 pm – 5:10 pm

Lightning Poster 2:  Targeting alphaVbeta3 Integrin to Develop Therapeutic Agents against Allergic Diseases

Kenji Izuhara, Japan

5:10 pm – 5:15 pm

Lightning Poster 3:  Development Of T Follicular Helper Cell 13s Is Restrained And T follicular regulatory cells is promoted by Prostaglandin I2 In Allergic Airway Inflammation

Allison E. Norlander, United States

5:15 pm – 5:20 pm

Lightning Poster 4:  The RNA Binding Protein Insulin Growth Factor 2 Binding Protein 3 (IGF2BP3) Is A New Inhibitor Of IL-13/IL-4 Signalling In Human Bronchial Epithelial Cells And A Novel Biomarker Of T2 High Disease

Onofrio Zanin, United Kingdom

5:20 pm – 5:25 pm

Lightning Poster 5:  Multiomics Analysis Identified IL-4-Induced IL1RL1⁺ High Eosinophils Characterized by Prominent Cysteinyl Leukotriene Metabolism

Koichi Fukunaga, Japan

5:25 pm – 5:30 pm

Lightning Poster 6:  Siglec-9 Expression On Mast Cells Contributes To Modulation Of Mast Cell Function In A Mouse Model Of Allergic Airway Inflammation

Adrian Piliponsky, United States

5:30 pm – 7:30 pm

Poster Session Reception

5:30 pm – 6:30 pm

Rapid Induction of Type-I Interferons by the OM-85 Bacterial Lysate Reduces Alternaria-Dependent Eosinophil Recruitment to the Airways

Vadim Pivniouk, United States

Investigating the Role of TNFSF14 (LIGHT) in Endothelial Cell Dysfunction in Eosinophilic Vasculitis

Haruka Miki, Japan

Perfluoroalkyl & Polyfluoroalkyl Substances (PFAS) Levels and Atopy Throughout Early Life

Carolyn H. Baloh, United States

PD-L1+ Neutrophils Impede Inflammation Resolution and NET Degradation During Influenza-Triggered Asthma Exacerbations in Mice

Thomas Marichal, Belgium

The Memory of Early-Life Skin Inflammation Induces Tissue-Resident ILC2 Expansion and Promotes Adult Atopic Dermatitis Relapse in a Neonatal Mouse Mode of AD-like Skin Inflammaton

Masato Tamari, Japan

Impact of Hyaluronic Acid Synthesis During Acute Inflammation and Contact Hypersensitivity Reactions – Lessons from Has-Knockout Mice

Jan C. Simon, Germany

IL-33-mediated Inflammation is Female-Dominant and Sex Hormone-Dependent

John J. Ryan, United States

Visceral Adiposity and Insulin Resistance Define A Metabolically-Driven Endotype of Obesity-Associated Asthma

Alessandra Tomasello, United States

Atopy And Neuregulin-1 Promote Survival From Respiratory Viral Infections Through Distinct Mechanisms

Mitchell H. Grayson, United States

Macrophage Senescence Drives Allergic Airway Inflammation and Is Suppressed by PPAR--γ Activation

Peisong Gao, United States

Characterization of Circulating Extracellular Vesicles in Atopic Dermatitis

Pierre-Yves Mantel, Switzerland

Allergen Sensitization at a Young Age Induces Allergic Airway Inflammation in Aged Mice

Shin Ohta, Japan

Ozone Induced Airway Eosinophilia Was Associated With Interferon Gamma In Asthmatic Rhesus Macaques

Gursharan Kaur Sanghar, United States

Monocyte Chemotactic Factors in the Airways of Patients with Mild Asthma: Effects of an Inhalation Allergen Challenge

Harissios Vliagoftis, Canada

Secretory IgA Modulates Endotype-Specific Inflammation and Microbial Interactions in Chronic Rhinosinusitis

Valerie M. Hox, Belgium

ILC2-Driven Production of Innate IgE by B1 Cells Amplifies Type 2 Inflammation in Allergic Disease

Kazuyo Moro, Japan

Host UPF1 Is Required For The Antiviral Response Against Rhinovirus And Exploited For Adequate Viral Replication

Onofrio Zanin, United Kingdom

Proteomic Analysis of Nasal Secretions after Biologic Treatments in CRSwNP

Philippe Gevaert, Belgium

Atopic Dermatitis and Eczema in the Elderly Population are Distinct Entities

Dagmar Simon, Switzerland

6:30 pm – 7:30 pm

Eosinophil ETosis as a Contributor to the Disease Activity in Granulomatosis with Polyangiitis

Shigeharu Ueki, Japan

IgE-mediated Activation of Basophils Induces Release of the Granule Protein Recognized by the Antibody 2D7

Whitney Stevens, United States

GM-CSF-Primed Eosinophils Enhance Mast Cell Activation

Francesca Levi-Schaffer, Israel

Generation of A Novel Mast Cell Phenotype Platform for Establishment of Anti-Allergic Modality Screening and Desensitization Strategies

Yosuke Kurashima, Japan

Mast Cells and Eosinophils Interactions with Candida albicans in Systemic Candidiasis

Ilan Zaffran, Israel

The Role of Mast Cells in the Pathogenesis of COVID-19 Patients

Ilan Zaffran, Israel

Metabolomic Analysis of Mast Cell Differentiation Reveals Key Metabolites Associated with Mature Mast Cells

Marianna Kulka, Canada

Wnt Pathway Activation By GSK-3 Inhibitor Downregulates IL-33 In Airway Basal Cells Via A DEPTOR–mTOR Axis

Hiroki Kabata, Japan

IL4-Ralpha and IFN-gamma Opposing Signals Modulate Neutrophils

Paola Andrea Martinez Murillo, Switzerland

Surfactant Protein A Reduces Viral Load in Influenza Infection in Asthma and Induces the Expression of Toll Interacting Protein

Monica Kraft, United States

Interaction of Mast Cells and Group 2 Lymphoid Cells May Attribute to Idiopathic Pulmonary Fibrosis Via BAM8-22-MRGPRX1/PGD2 Axis

Yoshimichi Okayama, Japan

5-Hydroxyeicosatetraenoic Acid And 12-Hydroxyeicosapentaenoic Acid Regulate Basophil and Mast Cell Activation and Basophil Recruitment in Chronic Spontaneous Urticaria

Yoshimichi Okayama, Japan

Sustained Eosinophil Depletion Perturbs Levels of Inflammatory peTh2 Cells but Not Other Circulating Inflammatory or Regulatory T Cells

Fei Li Kuang, United States

A Newly Identified Rptoros-Raptor-mTORC1 Axis Couples Mitochondrial Function With mTORC1 Activity in Macrophages

Hans-Uwe Simon,  Switzerland

Long-Term Inhibition of Acute Allergy by Initial Immunological Cross-Regulation and Epigenetic Memory in Lung Stromal Cells

Christian Pasquali,  Switzerland

Traffic-Emitted Ultrafine Particles Disrupt Resolution of Allergic Lung Inflammation

Bruce D. Levy, United States

Glucocorticoids Modulate the Binding of mRNAs To Monosomes and Depend on The Levels of the RNA-Binding Proteins ZFP36L1 and ZFP36L2

Onofrio Zanin, United Kingdom

The Children’s Allergy and Asthma Data Repository (CADRE)

James E. Gern, United States

Real-World Association of Indoor Air Quality With Cough Frequency Using Objective Monitoring

Min-Hye Kim, Korea

Exposure To Micro- and Nanoplastics (MNP) is Linked to Sensitization Profiles in Children

Jan Pantlik, Croatia

Sex-Specific Epigenetic Modification Associated with Asthma

Joe G. Zein, United States

7:00 am – 8:00 am

Breakfast

8:00 am – 9:40 am

Oral Abstract Session 4: Lymphocyte Biology

Chair:  Hirohito Kita, United States

8:00 am – 8:20 am

Oral Abstract 15:  Pathogenic Subset of CD4⁺ Skin-Resident Memory T Cells Require CXCR6-CXCL16 Signaling for Their In Situ Maintenance in Allergic Dermatitis

Kenji Kabashima, Japan

8:20 am – 8:40 am

Oral Abstract 16:  The Role Of IgD In The Development Of Natural And Induced Tolerance To Allergens

Mübeccel Akdis, Switzerland

8:40 am – 9:00 am

Oral Abstract 17:  Stage- and Lineage-Specific Enhancer Elements of GATA3 Differentially Regulate Th2 and ILC2 Development in Allergic Inflammation

Hiroshi Nakajima, Japan

9:00 am – 9:20 am

Oral Abstract 18:  Germline-encoded Recognition of Peanut Allergens Underlies Structural Convergent Antibodies in Humans

Sarita U. Patil, United States

9:20 am – 9:40 am

Oral Abstract 19:  CCR8+ST2+ Tissue-resident Regulatory T cells Constrain Type 2 immunity to Environmental Allergens in the Lungs

Hirohito Kita, United States

9:40 am – 10:10 am

Break

Mapping the Neighborhood – Immune/Stromal Interactions Regulate Lung Immunity

Clare Lloyd, United Kingdom

11:00 am – 11:30 am

Lunch

mRNA Vaccines for Allergy

Marc Rothenberg, United States

12:45 pm – 4:30 pm

Optional Tour

5:00 pm – 5:30 pm

Poster Lightning Round 2

Chair: Tanya M. Laidlaw, United States

5:00 pm – 5:05 pm

Lightning Poster 7: Modelling C1-INH Deficiency in Hereditary Angioedema with Patient-Derived Expanded Potential Stem Cells and Gene Editing: Toward a Physiological Cure

Philip H. Li, Hong Kong

5:05 pm – 5:10 pm

Lightning Poster 8: Dietary Fermentable Carbohydrates Promote Mucosal Mast Cell-Dependent Visceral Hypersensitivity and Type 2 Immune Responses

Laurent L. Reber, France

5:10 pm – 5:15 pm

Lightning Poster 9: Regulation of Airway Epithelial Regeneration and Remodeling By Cholesterol 25-Hydroxylase

Nora A. Barrett, United States

5:15 pm – 5:20 pm

Lightning Poster 10: CK-CARE’s ProRaD Registry: A Multidimensional Pan-Omics Resource for Translational Research in Atopic Dermatitis and Comorbidities

Claudia Traidl-Hoffmann, Germany

5:20 pm – 5:25 pm

Lightning Poster 11: A Pilot Study of the Indoor Dust Microbiome in Homes of Children with Asthma

Augusto A. Litonjua,  United States

5:25 pm – 5:30 pm

Lightning Poster 12:  Understanding Asthma Phenotypes, Disease Heterogeneity and Severity

Eugene R. Bleecker, United States

5:30 pm – 7:30 pm

Poster Session Reception

5:30 pm – 6:30 pm

MY010: An Anti-Allergen Multispecific for the Treatment of Multiple Tree Pollen Allergies

Pascal Gasser, Switzerland

Grass Pollen Specific Immunotherapy Modulates the Purinergic Metabolism Pathway by Dampening Adenosine Deaminase in IL-10+ ILC2

Janice A. Layhadi, United Kingdom

Potency Of Dermatophagoides Spp SLIT Tablet Compared to US Standardized Mite in ID Testing

Désirée E. Larenas Linnemann, Mexico

Allergen Extract Potency as Measured in SPT Is Maintained in a Sublingual Maintenance Vial with a Mix of Three Non-Homologous Allergens of Pollens and Mites

Désirée E. Larenas Linnemann, Mexico

Novel Weekly Combined Symptom Medication Score to Assess Seasonal Allergic Rhinitis Burden and Efficacy of Immunotherapy

Michelle Huffaker, United States

Determinants of Mast Cell Priming Potency by Peanut Allergic Patient Monoclonal IgE Pairs

Scott D. Boyd, United States

Oral Desensitization to Peanut Differentially Affects IgE-Mediated Human Basophil Histamine Release and C-C Chemokine Receptor 2 Expression

Bernhard F. Gibbs, United Kingdom

Changing Allergen Immunotherapy Practice Profiles in Mexico

Claudia Gallego, Mexico

Tolerogenic Modulation of Humoral and Cellular Immune Responses by PQ Grass: Biomarker Results from a Pivotal Phase III Trial

Mohamed H. Shamji, United Kingdom

Etiologic Diagnosis of Seasonal Allergic Rhinitis Supported by Artificial Intelligence

Paolo M. Matricardi, Germany

Spatial Immunology: IgE Response Differences Through Network and Manifold Analysis

Sara Fontanella, United Kingdom

The Immunological Relevance of Roasting-Enhanced Complexation Of Peanut Storage Proteins

Ronald van Ree, Netherlands

Human IgE mAb Epitopes Associated With The IgE Repertoire To Fel d 1 For Design Of Immunotherapeutic Molecules

Anna Pomés, United States

Th1-Promoting Proteins In Birch Pollen: Evidence At The T Cell Level

Barbara Bohle, Austria

The Utility of Sensitisation to Inhalant Allergens in Asthma Diagnosis In Children – Findings from the RADicA Study

Clare S. Murray,  United Kingdom

The Updated Cross-Canada Anaphylaxis Registry (CRAFT): Demographics, Triggers, Co-factors and Management

Alexandre Ton That, Canada

Two Mechanisms of Severe Sting Anaphylaxis: Hereditary and/or Clonal Mast Cell Disorders versus High Allergenicity of Venom-Specific IgEs

Peter Korosec, Slovenia

Autoimmunity Related Markers are Lss Frequent in Patients with Mast Cell-mediated Angioedema

Marina Sabate Bresco, Spain

Frequency of Mast Cell Disorders in Long COVID

Mariana C. Castells, United States

Exploring Basophil Phenotypes and Functional Dynamics Across Mast Cell Disorders

Theo Gulen, Sweden

Tomato-derived Aromatic Compounds Amplify MRGPRX2-dependent Mast Cell Activation: A Mechanistic Link to Pseudoallergic Reactions in Chronic Urticaria

Katarina Stevanovic, Germany

Genetic Susceptibility to Iodinated Contrast Media-Related Anaphylaxis: A Microarray Gene Chip Study in a Korean Population

Yoon-Seok Chang, Korea

6:30 pm – 7:30 pm

Alfred Wolff-Eisner: A Pioneer in Immunology and Allergy at the Beginning of the 20th Century

Johannes Ring, Germany

Absence of Alpha-Tryptase Isoforms is Associated with Lower Risk of Severe Allergic Reactions in Individuals Allergic to Peanut and Cow’s Milk

Paul J. Turner, United Kingdom

Diversification Of Human Milk Oligosaccharide Mixes Increased Their Ex Vivo Impact on the Fecal Microbiome of Infants with Cow’s Milk Protein Allergy

Sophie Nutten, Switzerland

Asymptomatic Sensitisation to Food Allergens – How Common is it in UK Adults?

Angela Simpson, United Kingdom

Role of Human Milk in Development of Food Allergy

Kirsi M. Jsrvinen-Seppo, United States

Milk Allergen-Induced Eosinophil Activation in Eosinophilic Esophagitis: The IgG4 Pathway

Emily C. McGowan, United States

CRISPR/Cas9 In Vivo Screens for New Regulators of B Cell Activation and Plasma Cell Differentiation

Lesly Calderon, Germany

O3 Inhalation Induced Non-canonical IL-13+Il-17+ILC2s In Asthmatic Rhesus Macaques Is Associated with Airway Hyperresponsiveness

Angela Haczku, United States

Molecular Mechanisms Governing CD4+ Tissue-Resident Memory T Cell Regulation in the Pathogenesis of Chronic Allergic Disease

Kiyoshi Hirahara, Japan

Eosinophil-Derived Neurotoxin Is An Asthma Biomarker Linked To Wheezing Severity In Preschool Children

Niclas Rydell, Sweden

Clinical Characteristics of Difficult-To-Treat Allergic Bronchopulmonary Aspergillosis and Its Prediction Score

Koichiro Asano, Japan

Optoacoustic Visualization of Skin Barrier Changes During Topical Treatment in Atopic Dermatitis

Ulf G. Darsow, Germany

Dupilumab Modulates Type 2 Memory B Cells, T Cell Phenotypes, and Inflammatory Biomarkers in Pediatric Atopic Dermatitis

Willem Van de Veen, Switzerland

High-Dimensional Analysis of Type 2 Lymphocyte Dynamics During Mepolizumab or Dupilumab Treatment in Severe Asthma

Jenny M. Mjösberg, Sweden

Stratum Corneum Hydration Predicts Atopic Dermatitis Risk in Moisturized Infants: Secondary Analysis of a Randomized Controlled Trial

Kiwako Yamamoto-Hanada, Japan

Critical Pathomechanisms of NSAID-Exacerbated Respiratory Disease (N-ERD) Clarified by Treatment With Omalizumab, an Anti-IgE Antibody

Masami Taniguchi, Japan

Open-Label Clinical Trial to Evaluate the Effect of Intranasal Olopatadine/Mometasone and Azelastine/Mometasone on Histamine Reactivity in Skin Prick Tests – Pilot Study

Elsy M. Navarrete-Rodriguez, Mexico

Nasal Tissue Predictors of Post-Operative Nasal Polyp Recurrence in Chronic Rhinosinusitis with Nasal Polyps

Kathleen M. Buchheit, United States

Novel Anti-IgE Antibodies With Optimized Disruptive Efficacy Suppress Anaphylaxis In Vivo

Alexander Eggel, Switzerland

Phase 2b Trial Results of Rezpegaldesleukin: Novel Treg Inducing Biologic for Atopic Dermatitis

Thomas Bieber, Switzerland

7:00 am – 8:00 am

Breakfast

8:00 am – 10:00 am

Oral Abstract Session 5: Pathophysiology of Allergic Inflammation 2

Chair:  Milena Sokolowska, Switzerland

8:00 am – 8:20 am

Oral Abstract 20:  Epigenetic And Transcriptomic Mechanisms of ILC2 Memory in Allergic and Healthy Subjects

Rafeul Alam, United States

8:20 am – 8:40 am

Oral Abstract 21:  CFTR Signaling Restrains Th2 cell Development through a CFTR/IL-4/GATA3 Axis and Reduces Allergic Airway Inflammation

R. Stokes Peebles Jr., United States

8:40 am – 9:00 am

Oral Abstract 22:  Epithelial Tuft Cells Signal to Trigeminal Sensory Nerves to Direct Allergen-elicited Olfactory Remodeling

Lora Bankova,  United States

9:00 am – 9:20 am

Oral Abstract 23:  Tuft Cells Shape Airway Remodeling By Eliciting OXGR1- and SOX9-Dependent Stem Cell Programs

Nora A. Barrett,  United States

9:20 am – 9:40 am

Oral Abstract 24:  Metabolic Control Of The Innate Type 2 Immune-Tuft Cell Axis In The Gastrointestinal Tract

Caspar Ohnmacht, Germany

9:40 am – 10:00 am

Oral Abstract 25: Involvement Of Tuft Cells In The Pathogenesis Of Eosinophilic Gastroenteritis

Hideaki Morita, Japan

10:00 – 10:30 am

Break

10:30 am – 11:50 am

Oral Abstract Session 6: Metabolism and Microbiome

Chair: Erika Von Mutius, Germany

10:30 am – 10:50 am

Oral Abstract 26: Reduced ALDH2 in the Respiratory Tract Causes Dysregulated Alcohol Metabolism and Respiratory Reactions in AERD

Tanya M. Laidlaw, United States

10:50 am – 11:10 am

Oral Abstract 27:  L-Phenylalanine Orchestrates Th2 Cell Fate and Function in Allergic Inflammation

Milena Sokolowska, Switzerland

11:10 am – 11:30 am

Oral Abstract 28:  Asthma Increases Abundance and Metabolic Activity of Myeloid and Lymphoid Effector Cells in Adipose Tissue From Adults with Obesity

Katherine Cahill, United States

11:30 am – 11:50 am

Oral Abstract 29:  Gut Microbial Bile and Amino Acid Metabolism Associate with Peanut Oral Immunotherapy Failure

Susan Lynch, United States

11:50 am – 1:30 pm

Lunch

1:30 pm – 2:15 pm

CIA Business Meeting

The Evolution of Clinical Immunology

Zuhair K Ballas, United States

3:00 pm – 3:30 pm

Break

3:30 pm – 5:10 pm

Oral Abstract Session 7:  Mast Cell-associated Diseases and their Treatment

Chair: Maria Jenmalm, Sweden

3:30 pm – 3:50 pm

Oral Abstract 30: Skin Mast Cell-Derived Exosomes Exhibit A Unique MicroRNA Signature And Participate In Cell-Cell-Communication

Torsten Zuberbier, Germany

3:50 pm – 4:10 pm

Oral Abstract 31: Expression of KIT D814V in Murine Hematopoietic Stem Cells Results in a Mastocytosis Phenotype of Systemic Mastocytosis with an Associated Myeloid Neoplasm

Karin Hartmann, Switzerland

4:10 pm – 4:30 pm

Oral Abstract 32: The Bruton’s Tyrosine Kinase Inhibitor Acalabrutinib Aborts Ongoing Acute Food-Induced Anaphylactic Reactions in Humanized Mice

Melanie C. Dispenza, United States

4:30 pm – 4:50 pm

Oral Abstract 33: Dual Targeting of MCs and TSLP with the Bispecific Antibody CDX-622

Diego Alvarado, United States

4:50 pm – 5:10 pm

Oral Abstract 34: Dermal Fibroblast–Mast Cell Crosstalk Promotes Hyperreactivity in Atopic Dermatitis via NF-KB and EGR1 Pathways

Anna Di Nardo, United States

6:30 pm – 9:30 pm

Gala Dinner

7:00 am – 8:00 am

Breakfast

8:00 am – 10:00 am

Oral Abstract Session 8: Treatment of Allergic Diseases

Chair: Alkis Togias, United States

8:00 am – 8:20 am

Oral Abstract 35: MY006: A Trispecific Antibody Blocking Four Allergenic Epitopes for the Treatment of Peanut Allergy

Pascal Gasser, Switzerland

8:20 am – 8:40 am

Oral Abstract 36: Fel d 1-Expressing Plant-Derived Bioparticle As A Novel Treatment For Cat Allergy

Janice A. Layhadi, United Kingdom

8:40 am – 9:00 am

Oral Abstract 37: Evolving Criteria in the Diagnosis of Smoldering Systemic Mastocytosis: Insights from the PIONEER Study

Mariana C. Castells, United States

9:00 am – 9:20 am

Oral Abstract 38: Targeting Sodium Channel (NaV) Subtypes to Treat Allergen-Induced Respiratory Symptoms

Bradley J. Undem, United States

9:20 am – 9:40 am

Oral Abstract 39: Ara h 2-Expressing Cucumber Mosaic Virus-Like Particle (VLP): A New Generation of Hypoallergenic and Tolerogenic Therapeutic Vaccine for Peanut Allergy

Mohamed H. Shamji, United Kingdom

9:40 am – 10:00 am

Oral Abstract 40: The Precision Interventions for Severe and Exacerbation-Prone Asthma Trial: Study Design and Initial Results

Steve N. Georas, United States

10:00 – 10:30 am

Break

Dendritic Cells in Atopic Dermatitis: A Promising Target to Reach Disease Modification?

Thomas Bieber, Switzerland