Light Minutes of the 13th Symposium
of the Collegium Internationale Allergologicum which was held in Konstanz, West
Germany in late July, 1980
GEOFFREY B. WEST

K. Ishizaka |

Geoffrey B. West |
Amid glorious surroundings of
the old German Town of Konstanz, the meeting in Germany opened alongside Lake
Konstanz in a converted 12th Century Monastery. Fancy monks talking about
"Cellular Interactions in Allergy"!
After a highly successful
welcome reception on the terrace and in the cloisters on Sunday, July 27th,
1980, the meeting got under way on Monday at 9:00 A.M. with a brief introduction
of the "Regulation of the IgE response" by - Vice-President Ishizaka.
Then came the Fifth Carl Pansmitz Memorial Lecture presented by Zoltan Ovary,
entitled "IgE production and suppression in mice". This was well
presented verbally but not visually - only a teething problem, really, for
the organisation of the meeting was first-class. The weather was good too, the
views over Lake Konstanz being superb, but the mosquitoes - more about
them later! After much talk about "Regulation of IgE responses", the
coffee break came - and we all had to pay 2 DM per cup. Later this was
changed to being free - but not until the organizers had said that they
have no knowledge whatsoever about coffee costs!
Then came member Sehon’s
presentation which contained such comments as:
- I have the Human Black Box
to direct you;
- the Ig molecule gets coupled
to things like whiskers; and
- let’s use abbreviations
like RAG-PEG, PEG-RAG, ANTI-RAG-15, AN-TI-RAG, ANTI-PEG, ANTI-PEG-15 and so on.
After a real German lunch, we
continued regulating the IgE response. I recall the secretary once saying
"I cannot neither see you nor hear you" to a guy talking from behind a
pillar. How many negatives did he really use?
And so to Monday evening which
was free except for the General Business Meeting of the C.I.A. when we discussed
"Finance, New Members and Future Events". That evening, some of us
found that beer cost 4 DM inside but only 3 DM outside if you put up with the mosquitoes!
I liked Tuesday on
"Delayed Type Hypersensitivity", for here were heard 44 times the
phrase "As we can see" (22 from 1 author alone) and several "We
think it is a reasonable dose". Just before coffee - now free, at
last member Goodman, starting off on his talk, was able to tell us "I’ve
just been handed a note to say that my time is up. So I will just have time to
thank the organizers for inviting me here before I show a few slides".
After coffee, the only point of interest, to me at any rate, was the fact that
member Askenase found histamine to activate suppressor cells in mice - but
he used 10-3 M histamine, a concentration which certainly makes the
gastric mucosa cells stand on end.
Tuesday afternoon was set aside
as a poster workshop on "Mediators of Allergic Reactions". I cannot
recall too much excitement here, except when member Pepys was incorrectly quoted
by someone and he immediately shouted "You’ve quoted me wrongly and my
guinea-pigs were all men". Another member was heard to say "I haven’t
the foggiest idea which of the 50 types of cells are involved in the reactions
in human lung".
Tuesday evening was the boat
ride on the Bodensee to Meersburg to hear the world-famous Knabenmusik in the
Schloß. We set out in sunshine but 20 minutes later a thunderstorm hit us when
we were nearly there. The heavens opened and we all got wet whilst disembarking
- all except the six who refused and stayed on the boat in the dry. These
six subsequently returned to Konstanz without the concert (which was first
class). A fine meal in the castle followed and we returned home about 11.
On Wednesday, we had parallel
sessions -"Clinical Evaluation and Standardization of
Allergens". I could not be in both places at once - but I did hear
that in the "Standardization" session one member showed a slide which
had three heavy finger marks on it, and all he could say was "Disregard my
fingers and concentrate on the data". In the other session, we all heard
that adenoids are removed solely to give the pharmacologist the mast cells to
play with. Not only that! The state of the MOON made a difference to the
reactivity of these human mast cells. This all arose from member Schmutzler
saying that his mast cells were better when the adenoids were removed at -
night - yes, even at midnight when the surgeon was on double pay! You
could even study diurnal variation in histamine release using these cells.
The ladies programme was well
organised by Mrs. de Weck and on Wednesday it consisted of a guided tour of
Konstanz. Four male members accompanied them and the highlight was the walk to
the top of the cathedral tower. It was a highlight because you paid nothing at
the bottom and ascended 400 steps to pay at the top and of course receive a
ticket to say you’d climbed the tower.
The boatride on the Bodensee on
Wednesday afternoon was superb. We even had a guide speaking from the bridge of
the boat. This was of course Mrs. de Weck who told us all about the Mainau
Island and the castle, now the property of Princess Bernadette of Sweden. It was
a glorious leisurely trip and we all enjoyed the sunshine and the gardens. Home
again and so to the CIA dinner in the banqueting hall in the evening. This
started with drinks out in the open, marred only by the mosquitoes which really
bit you. I recall one lady being bitten on the chest and crying out for help
- she wanted some ointment and someone to rub it on. Needless to say, CIA
members by the dozen offered help to rub it on . Needless to say, CIA members by
the dozen offered help to rub it on but they had no ointment. The buffet
followed - and a whole host of food was available. New members were
introduced -we had the minutes of the New Orleans meeting - and we
had dancing. All in all, a great evening.
Thursday morning was exciting
- "What’s new in Allergy?" Leukotrienes was tops to begin with
and we heard all about LTA 4, LTB4, LTC4 and
LTD4. Then on to developments in the "Anaphylatoxin" field.
After coffee (free again), PAF was on the menu but conflict arose between USA
and France which did not end very comfortably. The two parties were still
arguing when time ran out.
What a meeting? Everyone said
it was superb and thanks go to members de Weck, Dukor and Rother for arranging
such an event.
|